• Supporting patients and families living with Cystic Fibrosis, through public awareness, skilled medical professionals, clinics and funding events.

  • Supporting patients and families living with Cystic Fibrosis, through public awareness, skilled medical professionals, clinics and funding events.

Testing for CF

Abdominal Sonar :: Dexa Scan :: Full Lung Function Test :: Sweat Test

Abdominal Sonar

Gastrointestinal manifestations of disease are present in most adults with cystic fibrosis. Radiologists are familiar with the classical imaging characteristics of end-stage pulmonary disease and the radiological findings of meconium ileus in neonates. As most patients now live into adulthood, recognition of the imaging appearances of abdominal disease is important to enable prompt diagnosis and treatment. Accordingly, this article presents typical imaging appearances of the adult gastrointestinal manifestations of cystic fibrosis.


Dexa Scan

Dual energy X-ray absorptiometry (DEXA), also called bone densitometry uses a very low dose of X-ray to measure bone mineral density (BMD) which is the amount of calcium and other minerals present in the bones. The DEXA scan is a quick, non-invasive, and painless method and is most often done to get the images of lower spine and hip region.


There are two different types of DEXA scanning devices:

  • Central DEXA: The central DEXA scanner is passed over lower part of your spine and hip when you are lying on the X-ray table. It is the most reliable test to predict the risk of fractures.
  • Peripheral DEXA (p-DEXA): The peripheral DEXA device is a smaller machine that is used to measure bone density of the bones in periphery, such as the wrist, heel or finger.


A DEXA scan is used to diagnose osteoporosis, a disease in which bones become fragile and more likely to get fractured. It is highly recommended to undergo a DEXA scan in individuals who are at risk of developing osteoporosis. The risk factors for osteoporosis include:

  • Women aged above 65 and men aged above 70 years
  • A fracture following a minor fall or injury
  • Other disorders such as rheumatoid arthritis, chronic kidney disease, and eating disorders
  • An early menopause
  • Prolonged use of corticosteroid therapy for more than three months
  • Cigarette smoking
  • Previous hormonal treatment for prostate cancer or breast cancer
  • Loss of height due to vertebral compression fracture
  • Family history of osteoporosis
  • Excessive alcohol intake

The DEXA machine transmits two X-ray beams with different energy levels through the bone being tested. Soft tissues absorb one of the energy level and the remaining is absorbed by the bone. The bone mineral density is measured based on the difference between the soft tissue absorption and the total amount.


Normally, there are no restrictions on eating prior to the test. Calcium supplements should be discontinued 24 hours before the test. Women who are pregnant should always inform their physician or X-ray technologist.

During the central DEXA examination, you will be asked to lie still on your back on an X-ray table. The scan usually takes between 10 to 30 minutes. A detector arm of the device will slowly pass over the region of your body being measured. Generally, central DEXA scan measures bone density in the hip and spine region.

Peripheral DEXA scans are more simple in which your finger, hand or foot is kept in a small device that gives the bone density reading instantly.

Test results will be in the form of two scores:

  • T score: It is the comparison of your bone density with that of a young healthy adult. A T score of -1.0 or above is considered normal. A score between -1 and -2.5 indicates osteopenia (low bone mass). A score below -2.5 indicates osteoporosis.
  • Z score: It is the comparison of your bone density with that of other people of same age, sex, and race.


Full Lung Function Test

The Lung function test (also called pulmonary function tests) checks how well your lungs work. The tests determine how much air your lungs can hold, how quickly you can move air in and out of your lungs, and how well your lungs put oxygen into and remove carbon dioxide from your blood. The tests can indicated lung diseases such as Cystic Fibrosis and measures the severity of lung problems. This test is commonly use to check how well treatment for a lung disease is working.

Full Lung Function Test

Other tests-such as residual volume, gas diffusion tests, body plethysmography, inhalation challenge tests, and exercise stress tests-may also be done to determine lung function.


Spirometry is the first and most commonly done lung function test. It measures how much and how quickly you can move air out of your lungs. For this test, you breathe into a mouthpiece attached to a recording device (spirometer). The information collected by the spirometer may be printed out on a chart called a spirogram.


Sweat Test

A sweat test measures the amount of chloride present in the sweat. In the first part of the test, a colorless, odorless chemical (pilocarpine) and a little electrical stimulation is applied to a small area of an arm or leg to encourage the sweat glands to produce sweat. A person may feel tingling in the area, or a feeling of warmth.

Sweat Test

Once the sweat is collected on a piece of filter paper or gauze or in a plastic coil. The sweat sample is sent to a hospital laboratory to measure how much chloride is in the sweat. The sweat test usually takes about an hour, but it may take longer.

People with CF have more chloride (a component of salt) in their sweat than people who do not have CF.For a child who has CF, the sweat chloride test results will be positive (showing a high chloride level) shortly after birth. A baby has to sweat enough to do the test. Full-term babies usually produce enough sweat by 2 weeks of age.